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Introduction Keratoconus is an idiopathic and progressive disease, where the cornea develops an irregular and conical shape, being the most common form of dystrophy or corneal ectasia, developing between the age of 12 and 20. In Mexico, the epidemiological information about the pathology is scarce. Purpose To explore the epidemiology of keratoconus in Mexico among adolescents, and to compare the prevalence with international literature reports. This study identified associated pathologies and examined the management of patients. Methods A retrospective study was conducted in an ophthalmology clinic; 500 charts were randomly selected from patients between 10 and 20 years of age in order to acquire information about the identification of the patient; the patient's gender, birthday, and age; three principal diagnoses at the first visit; as well as refraction and visual acuity in both eyes. After this, statistical analysis of the information was done.